Royal Air Force Typhoon fighter aircraft have operated alongside French warplanes in a coordinated attack against an underground arms cache in Syria operated by the IS group, as stated by the UK's MoD.
The facility, identified by reconnaissance, was thought to be storing arms and explosives, the release indicated, and was positioned in hills just above Palmyra in Syria's central region.
"Our aircraft employed Paveway IV guided bombs to target a number of access tunnels providing entry to the depot... early reports suggest the strike was effective," the ministry announced.
There was no sign of any harm to civilians in the operation conducted Saturday night and each participating jet made a safe return, the ministry further stated.
The Typhoon fighters were supported by a Voyager aerial refuelling aircraft.
The Islamic State group - alternatively referred to as Daesh - enforced militant control over significant areas in Iraq and Syria before its territorial defeat in 2019.
"This operation shows the UK's leading role, and determination to operate in unison with allied nations, to eliminate any re-emergence of Daesh and their violent and radical beliefs in the region," Britain's Defence Chief the Defence Secretary said.
British military aircraft have conducted overwatch operations over Syrian airspace to "prevent any attempted comeback" of Islamic State subsequent to its routing at the Baghuz confrontation in 2019, the MoD reported.
"I want to thank all the members of British forces involved in this operation for their skill and their courage," Healey added. "They were among a great many British personnel deployed over the holidays. This mission, to take out militants who endanger our security, highlights how our armed forces are always on standby, all year round, keeping Britain secure at home and powerful internationally."
During December, the American forces executed what it called a "massive strike" targeting Daesh sites in Syria, following an ambush resulted in the deaths of two US troops and a civilian interpreter in Palmyra.
The UN says Islamic State still maintains between 5,000 and 7,000 militants in both countries.